Hey everyone – Tony here with my Compound 20 Review. As I mentioned on the Compound 20 homepage, this is a new supplement from USPLabs (creators of popular supplements Jack3d and OxyELITE Pro, among others), and is marketed as a “Leaning & Hardening Cocktail”.
Folks, I’m going to give it to you straight here. I love USPLabs (I am not an employee, rep, or otherwise affiliated with them in any way), but the official Compound 20 write-up has got to be one the most confusing things ever written. So I’m here to straighten things up.
“Table of Contents”
This is going to be long, so buckle in or get the printer warmed up.
First, we’re going to talk about what this potent natural supplement will do for you – both the good and the bad.
Finally, I’ll talk about what in the world this write-up / product description really means… because while this stuff is phenomenal, it is a tricky to understand, even for a seasoned bodybuilder like myself who’s seen his fair share of supplements.
Here We Go Again…At this point, we all know that USP is an aggressive company that hypes the living crap out of their products. This could be seen for better or for worse, because they run the risk of over-hyping a product. At the same time, you do need to get the word and excitement out if you want to be a successful company – and USPLabs is clearly that – and it’s mostly fueled by repeat business. Keep that in mind.
USP makes unique, natural formulas with patented extraction processes in GMP Certified Facilities. They also follow DSHEA Compliance (Under the FDA’s Dietary Supplement Health and Education Act of 1994). At the end of the day, nearly the entire line-up of supplements work like crazy, which is especially clutch since it’s composed of completely natural supplements.
Cliff’s Notes for the Lazy
The end result of this whole review is basically this: Compound 20 is the real deal, both from a scientific standpoint AND from a product usage standpoint (100+ people of all walks of life have run succesful logs on it at this point!). Confusing product write-up aside (which we aim to fix here), IT WORKS.
In fact, if you’re going to jump in and buy it — and I encourage you to read this whole review before you do so — you should probably jump in with two bottles and save yourself on shipping from the second order. Because you will want to keep your run going. All natural supplements take a few weeks to kick in, and weeks 3 and 4 are where it all unfolds with C20. An 8 week run is where sparks will truly fly.
So we’re going to explain what’s happening in English that you can understand. It’s going to be long, but it’s interesting as hell, and it helps you gameplan how to use it most effectively and what to expect.
Let’s have at it.
My Compound 20 Review
Compound 20 is best described as a strength-inducing leaning agent, as it’s helped myself and nearly everyone else shed bodyfat regardless of diet! Obviously, clean eating is going to get you better results, but if you’re a “carbophobe” who fears carbohydrates, you won’t be by the end of your C20 run.
Get Compound 20 at:
In fact, you’re going to need complex carbs – and a lot of them early in the day – and you’ll learn why soon.
First, let’s talk results. What did C20 do for me and over 95% its users? In short, this capsule-based supplement brings the following benefits:
- Crazy fat burning properties – this stuff works better than most stimulant-based fat burners I’ve tried, and it’s not even marketed as a “fat burner”! But if you’re in a dieting/cutting phase and you stack it with something like OxyELITE Pro, you are going to shed fat like never before!
- Added muscle mass – I somehow lost bodyfat yet gained muscle during a “maintenance bulk”! Those who take it during a seriously heavy bulking / weight-gaining phases do even better though — Just get ready to eat and drink like crazy!
- Strength Gains – With regards to something that is non-hormonal like Compound 20, you will not find a better supplement to boost your strength (except perhaps creatine). I seriously set 5 PRs in one day during the peak of my cycle with C20! I was not the only one.
- Stimulant-free energy! I’ve been taking Compound 20 while off all stims (yeah, I know, life usually sucks without Jack3d, but you do need to cycle off of it – and Compound 20 makes that transition EASY)!
This means that, yes, I set those PRs without an ounce of Jack3d or other caffeine in my body. I honestly didn’t expect this.
This is not your “typical kind of energy” if that’s possible to explain. It’s different. Training becomes more explosive. Sprints and HIIT become faster. We’ll see why below as I break down the ingredients for you.
The Side Effects Are Really Benefits!
And best of all? The only two “side effects” I experienced were massive amounts of hunger/thirst and an intensified libido! If you take Compound 20, get ready to drink water, and drink a lot.
Every last reviewer felt this, and there’s a reason – whenever we increase anabolism, the body is naturally responding with an increased appetite to yield the muscle growth (hypertrophy) that you’re pushing it towards.
Not only that, but one of the ingredients is acting as a GDA (Glucose Disposal Agent), and is shuttling complex carbs into your muscles. This is also called “nutrient partitioning” (supplements in this family are named “nutrient partitioners”).
To explain the thirst, for every carb stored in the muscle tissue as glycogen, it shuttles 2.7g of water with it as well. This adds up when you’re lifting heavy, so listen to your body and DRINK. I’ve had days where I drank nearly 200oz of water. I kid you not.
Kind of annoying? Yes. Epic muscle growth for a natty supplement? YES.
Now, that said, the beta testers and I all realized that this REALLY SHOULD be taken with complex carbs, at least at first until you’re ready to start experimenting. USPLabs has some incredible products that kick ass on a Fasted Training Protocol (FTP) (Jack3d, Modern BCAA, PowerFULL, and Prime to name a few), but I honestly don’t think this is one of them.
If you don’t eat a halfway decent of complex carbs — especially in your morning pre-workout meal — you could get sluggish, a bit faint, and irritable. This is because the GDA effect of Compound 20 is clearing your blood sugar and storing it into your muscles as glycogen.
If you don’t have enough “in the tank”, you’re not going to enjoy life until you force some solid food down. This feeling can happen within 20 minutes, so take C20 mid-meal. Otherwise, you’ll want to claim the faintness as another side effect – but that is your fault, not USP’s!
My favorite complex carbs? Yams / Sweet Potatoes, Oats, and Brown Rice. But don’t take them too late in the day, or else you might experience bloating. After the second dosage of Compound 20, it’s time to “shut the carb machine down”, or at least slow it down.
You’ll need to experiment with this, and it will honestly take a couple weeks to really get it down. This is why an 8-week run is going to suit you best. By that time, you’ll have it down to a science, and the effects will have amplified themselves well.
You Mentioned Libido…?
As far as the libido goes, about half of the testers felt this, and some of them even claimed it was “raging”. Tell your woman to get ready!
I am dead serious when I say this: During my Compound 20 review run, I was in the “honeymoon” phase with a new girlfriend. I’ve “honeymooned” before but I have NEVER been this much of a machine. I am seriously glad that I wasn’t single during this run (or unhappily married). Keep that in mind – you’re going to crave trouble. It was f’ing awesome.
(As to whether women are feeling the libido boost, we’re still uncertain).
What Compound 20 is NOT
Before we get into the ingredients and my personal Compound 20 Review, let’s clarify a few things:
- This is non-hormonal, or at least not to a strong degree at all. You do not need post-cycle therapy (PCT) after taking it to ease your system off. It does not boost your testosterone levels, except perhaps indirectly due to more intense workouts and anabolism.
- This is not Clen. I am sorry USPLabs, but much of their product description compares it to Clen, which is short for Clenbuterol and is a fat-burning agent that is not legal.Clen is illegal for a reason – it’s simply insane and is similar to epinephrine and attacks your heart. It’s prescribed to help some with asthma conditions, but is definitely a thermogenic stimulant.The good news, however, is that it behaves similarly to a weaker version of Clen. We’ll talk about this, but to anyone who’s ever used Clen, you need to realize that this is not the same thing. That’s also a positive thing since Clen is a bit TOO insane, but USP Labs still found a way to target the receptors it works on.In short, I’m just trying to temper your expectations here. It’s amazing, but it’s not going to illicit illegal-drug-like effects.
- Compound 20 has some nutrient repartitioning properties, but it does not manipulate insulin or spike insulin levels.
- It has some stimulant-like properties, but is completely stimulant free. This means you can stack it with some awesome stuff to bring fat-loss and workout intensity to the next level!
- C20 does not seem to be a recovery agent, as I was incredibly sore a lot of the time, despite taking BCAAs throughout. I was also lifting my most, but had this been a test booster, I don’t think I would have been this sore. I was fine with this. Many others are experiencing the same thing.Point being, your body is going to be shredding muscle up and building it back up, and you’re going to be sore. Eat big and deal with it
First, let’s cut to the chase – I’m 6’1 and began my run at 197lbs, 11% bodyfat. I finished at 204lbs, 9% bodyfat, and I wasn’t even on a strict cutting diet.
During Weeks 3 and 4, I broke PRs like crazy:
- Deadlifted 440lbs (yep – well over twice my bodyweight). I’ve never anything over 410lbs, so clearly I was stoked beyond belief.
- DB benches at 110lbs (each arm) @ 5 reps. My chest could have gone more, but my shoulder joints (my weakness) didn’t appreciate this and I seriously had to hold back!
- Weighted Dips: +100lbs for ~300lbs total, @ 5 reps. This one hurt for days.
- Weighted Pullups: +50lbs @ 4 reps. That 5th rep didn’t count but the PR did.
- Barbell Lunges – 200lbs @ 5 reps on each leg. I’m not sure if this is impressive to anyone. My hams and quads are comparatively weak.
The list goes on…
I must say that I’m not a fan of all of USPLabs’ beta testers stacking this with every damned supplement in their arsenal. OF COURSE they’re going to get great results! So I took the opposite approach.
This was taken during a completely stimulant-free run. Normally, that’d suck, but let’s be honest – I could supplement cyanide and I’d still have incredible workouts thanks to Jack3d. So I removed that from the equation completely.
So beyond Compound 20, I had the following weapons at my disposal:
- MTS Nutrition MACHINE Whey – This stuff tastes fantastic. My pre-workout meals with Compound 20 were typically a concoction of a cup of oats, 50g of Machine Whey, and 1 tablespoon of macadamia nut oil for some incredible MCTs.
- Modern BCAA – 10g during workout. Stacked with 5g of Athletic Xtreme German Creatine.
- Post workout, 40g of MTS Whey. If it was a morning workout (I switched exclusively to morning workouts – This is when I was most effective without caffeine), I added 20g dextrose to the whey too.
- 3 softgels of NOW Foods Omega 3 before bed
- 4 softgels of CLA (split at 2 caps with the meals, 2x/day). This DOES have fat-burning properties, but I supplement it every day regardless of what I’m doing, so I don’t think this .had much effect in my fat loss since it was already in my tack before we started.
I also take a few stim-free cognitive enhancers like N-Acetyl L-Tyrosine and Piracetam after working out to get focused for work, but those don’t have anything to do with strength/muscle gains or fat-loss.
And that’s it. Seriously. No pre-workout or pump product at all, which is what I used to set all of my previous PRs. Unbelievable what will happen if this gets stacked with Yok3d or Jack3d.
The first week was definitely weird. I felt nothing the first three days, and was starting to wonder when anything would happen, if ever.
On day 4, I had an explosive workout and started to “feel something”. I was stim free, but there was an energy effect that was giving me much more burstful fast-twitch workouts.
I also quickly discovered the GDA / nutrient partitioning effects of Compound 20, as I tried to take it on an empty stomach pre-workout with just Modern BCAA and felt freaking awful until I forced down a shake with oats. Instantly, I felt the carbs zip me back up. Some beta testers are doing fine with a fasted training protocol – not me. I think I am too carb sensitive, and that’s why I issue caution on it.
The beginning of week two was weird. The thirst and hunger started hitting me hard, and after fighting it for a day, I learned from others’ logs and just started going after it in the kitchen.
The bad news was that one day at the end of the week, I was carbing all day long, well past my “4pm carb window” that I set for myself. The next day, I was bloated as shit. Lesson learned – no latenight carbs with this one and all of its water requirements unless you are on an “onslaught bulk” and simply don’t care.
Strength going up… recovering from a shoulder injury had me holding back a bit, but screw that. Showtime was starting and I wasn’t missing out on my two weeks left.
Two days after the nasty bloating incident, I’m with the lady friend, take off my shirt, and she just says “Wait. I need to stare at your definition for a while first”. Awesome compliment, and also weird – two days before I was bloated as all hell.
Fact is, this stuff seriously listens to whatever you tell your body to do. I’m pretty confident that I could properly cut OR bulk like crazy at this point. Nighttime meals at this point are just absolutely loaded with protein and green veggies and I’d wake up feeling tight and God-like.
Sleep cycle was GREAT during this time. Honestly, I think this is more to do about my adrenals resetting since I was really screwing myself up with a high caffeine intake before this run (I was at 500mg/day and it was time to get off).
First PRs start surfacing at this point.
Week 4 – GAMETIME
At this point, I got my “Compound 20 System” completely down. Wake up at 5:30. Eating my pre workout meal at 6 with C20. In the weightroom before 7, obliterate the f’ing place, and out of there before 8, post-workout shake in hand.
Eat eat eat eat eat. Drink drink drink drink drink.
Second dosage of Compound 20 with yams or brown rice at 2 or 3pm.
Drink drink drink drink drink.
Dinner consists of animal protein (I’m not a “lean beef eater” – bring on the fats here as long as they come from pastured animals and grass-fed cows), fish, and craploads of spinach/kale/broccoli/bok choi/anything colorful along with some almonds, walnuts, and/or pecans. Olive oil, bacon grease, beef tallow, coconut oil (my favorite)… you name it. I killed it all.
Drink drink drink drink drink.
Casein shake before bed if it’s a workout day, fish oil, and sign out.
PRs dropped like flies. The weightroom was my domain. Hell, even cardio was my domain. Week 4 was some of the most fun. I’m glad the girl enjoyed the sex as much as I did, because I literally treated her like a workout too. She was okay with it (I think? Haha…)
Compound 20 Review – End of the Run Conclusions
Sadly, I feel like I wasted some time figuring out WTF was going on with this stuff, especially during week 2, and that’s why I want to impart some of my experiences regarding the carbs and nutrient timing to you.
Additionally, I was flat out bummed this came to an end. I wasn’t done. I seriously think I could have continued the PR-setting.
I also think YOU can do better without the stumbling blocks I hit, and the fact is that most natural supplements take 6 weeks to really kick in. That’s why next time, it’s going to be an 8-week run. Buy two bottles, you won’t regret it.
I’ll admit that I’m relieved that I’m no longer needing to drink boatloads of water, but now that I’m done with the run, I’m no longer gaining weight or muscle mass and had to tighten my diet up.
The good news – I’m still over 200lbs (between 202 and 203 this week) two weeks after the run is done. The results are STICKING!!! No new PRs, but I’m no weaker either!
LOOK AT THIS. Kameron Ross absolutely DESTROYED his C20 run:
Holy crap moment at the 2:00 mark! I was happy about deadlifting 400lbs – Kam puts up 600lbs TWICE. Good God. And his before and after pictures at 2:45? Unbelievable!
Now, you might wonder how he finished his run on Day 25. As he goes on to mention in the video, he started taking 6 capsules on training days after his first two weeks.
Is this recommended? No. USPLabs wants everyone to stick to the dosing protocol.
Did it work? Obviously… yes.
Should you do it? I’d say no unless you’re an advanced USPLabs supplement user and have your diet and water consumption completely in line.
Kameron is sponsored by Valley Sports Nutrition.
Update on Kameron: He ended up deadlifting 622.8lbs in a competition. Good God. Thanks USP!
Time for the technical stuff. But first, here’s what’s amazing, in true USPLabs fashion:
Only 3 Ingredients.
Unlike most other big-name supplement manufacturers that we won’t mention here, USP doesn’t follow the kitchen sink formula, just “hoping” that something will work for you. They identified three amazing leaning ingredients, and put them to work.
Jack3d has 6 ingredients and no nonsense fillers. OxyELITE Pro is the same. Compound 20 follows the tradition of these award-winning supplements.
But before we get into the actual ingredients in Compound 20, we have to discuss the processes that they’re working on. If you already know this stuff, you can skip down below, but it’s good to understand.
Understanding cAMP and the Beta-2 Adrenoceptor
cAMP, or cyclic adenosine monophosphate is an important messenger in your body. It’s derived from ATP (adenosine triphosphate), which is well-known for being increased by several supplements such as creatine.
The subsequent cAMP created is very important for the processes involving hormones such as epinephrine, which is highly involved in “fight-or-flight” situations involving lots of adrenaline. What happens is that this cAMP activates something known as protein kinase A in your cells, and THAT process regulates the metabolism of your sugars and fats.
The metabolism of sugars and fats? Now we’re speaking some clear language.
This, of course, means, cAMP is involved in…
Now lets talk about the receptors that make this whole process happen. After all, something needs to sense the compounds outside, “receive” them, and activate the processes they cause.
The Beta-2 Adrenergenic Receptor is one of the three beta-adrenergenic receptors. These receptors get targeted by noradrenaline (norepinephrine) and adrenaline (epinephrine). Many of your cells have these receptors. When they’re activated, you get the flight-or-fight response – increased heartrate, energy gets mobilized, and bloodflow moves to the skeletal muscle to get ready for a potential battle or escape.
This process, of course, burns a lot of energy (ie burns fat!) and also gets you amped up for battle (or workout!). The process also avoids any muscle breakdown (consider this a very awesome side effect), as it gives the muscles everything they need to function highly for as long as possible.
So what does that have to do with cAMP mentioned above? Well, the problem is that hormones like adrenaline don’t actually pass through the cell membrane. They ACTIVATE processes, but once they are at the door and turn the key, they are done. On the other side, cAMP does the heavy lifting. This is why cAMP is called a “second messenger”.
So what we want are not only healthy receptors, but enough cAMP on the inside to get the job done for the duration of a crazy workout and a stressful day that includes recovery.
Obviously, our bodies can’t do all of this forever. But we can give them a boost!
So when this was whole process was discovered, leave it to the bodybuilding community to find some ways to “antagonize” these beta-2 receptors and get all these amazing responses going. And this is where we introduce Clen, short for Clenbuterol.
What’s the Deal with “Clen” in the Compound 20 Description
USPLabs keeps mentioning Clen in their product description. This is a banned asthma drug that was found to get those beta-2 receptors activated…. and then some! In short, this shit is way too crazy and fires ALL sorts of hormonal receptors – not just the beta-2 ones, but several more – and it causes a slew of terrible side effects because it is just not selective and tricks your body into mimicking all sorts of ridiculous hormonal situations. One such situation is that it hits beta-1 receptors which are located on the heart – NOT good!!
Thus, Clen’s side effects include extreme jitters all the way up to tremors, cramping, tachycardia (from the beta-1 receptors on the heart), and feeling like total crap after using it for a short amount of time (your body can REALLY only handle so much of this overly insane fight-or-flight response activity!).
For this reason, it’s completely banned by the FDA in America. In fact, it’s also illegal to feed it to animals, as they will then cause human food poisoning (China has been guilty of this – eat LOCAL, grass-fed beef!) Anyway, Clen is that potent and you don’t want it anywhere near your body.
But the fact is… the part where Clenbuterol started antogonizing beta-2 receptors turned a lot of heads, because that part DID work – it does cause fat loss without muscle-loss. It’s simply not worth the risk (both healthwise or legalwise).
So how can we fire ONLY the beta-2 receptors — just a little — and not the rest? How can we make a “safe, selective Clen”?
Re-Introducing USPLabs – The guys who have the best thing yet in Compound 20 – and it actually comes from DARK CHOCOLATE. No kidding!
So now we have that all settled, we’re ready get down to business and talk about the actual ingredients and what they do for you:
As hinted above, the first two ingredients actually come from the cocoa plant. You know how very dark chocolate has many purported health-enhancing effects? Well, these two ingredients take that idea to the next level.
In 2005, a study was published showing that N-coumaroyldopamine and N-caffeoyldopamine increase cAMP via beta 2-adrenoceptors.
When this was discovered, you can imagine what happened – a race to figure out if anyone could properly extract it from cocoa (specifically theobroma cocao), and if it was safe to take.
USPLabs, the kings of natural compound extraction, have won that race. But what everyone is seeing is just how amazing these beta-2 agonists really are. They are just as potent as the prescription drugs that we cannot (and don’t want to) take, but aren’t affecdting other receptors that fire off other, dangerous hormonal processes!
This pathway is also known to work on insulin and possibly IGF-1 as well.
Even better – these studies were done in vivo, which means on whole, living organisms. Not in a test tube (ie in vitro). This is big news as its one less thing for us to worry about translating to real life. I believe it after my run.
Beyond that, another study done on Clenbuterol and other beta-2 adrenergenic agonists shows that these types of compounds increase how much mTOR (mammalian target of rapamycin) gets activated. This is another type of protein kinase, but instead of regulating the metabolism of fats and sugars, it actually regulates GROWTH and protein synthesis and hypertrophy (muscle building).
Take it with Leucine-rich BCAAs such as Modern BCAA (best taken when fasting and/or during your workout) and you’ll see incredible results in muscle retention and growth!
So, while study #2 wasn’t done on N-Coumaroyldopamine itself, similar beta-2 adrenergenic agonists do, in fact, do increase mTOR and give you more possibilities of muscle growth. So there’s a great chance that N-Coumaroyldopamine does this as well.
But DOES it work in this muscle-building sense, or does it only work on fat burning? See the reviews for yourself — Compound 20 does BOTH.
Normally, when a supplement bills the “lose fat AND build muscle” thing, it’s BS. But this is legit from both an indirect scientific standpoint as well as a human testing review standpoint!
A nice chart of the process above is shown. PKT = Protein Kinase.
This ingredient gets listed alongside N-Coumaroyldopamine on the product description because it is very similar. Study  uses both of these together.
So basically, everything mentioned above, including the graphic, also applies to N-Caffeoyldopamine.
The basic differences between these two are that N-caffeoyldopamine is the “weaker” of the two, and N-Coumaroyldopamine is harder to extract and nearly impossible to find anywhere on the market besides in Compound 20. Thankfully, N-Coumaroyldopamine is also listed first on the ingredient label, so there’s more of it. USP doesn’t skimp on the good stuff.
You can see this on the picture to the rigth and how much cAMP production they make. USP is using the two natural beta-2 agonists from cocoa that are the most powerful!
This information is provided at , which is not actually listed by USPLabs in their product description but is a great piece of information.
Compound 20 Review – Symplocos Racemosa Extract (standardized for triterpenoids)
Symplocos Racemosa Extract is actually the first ingredient listed, so there is a higher amount of this than each of the above two ingredients. This is what is doing all of the “glucose disposal” / “nutrient partitioning” mentioned above. In even simpler terms… this is why C20 makes you so damned thirsty and needs to be taken with carbs.
In layman’s terms, Symplocoos racemosa first stops the cAMP from degrading, making it last longer. This is extremely synergistic with the above two ingredients for the obvious reasons – two kickstart the creation of cAMP, and this then keeps things going – long after your workout or dosage is taken.
But at that point, you know that this explanation isn’t enough for me. So this extract is “standardized for triterpenoids” – huh?
What’s this Triterpenoids Business?
Triterpenoids come from terpenoids, which are found in all living things, but are especially common in plants. Terpenoids are what give such great healing powers (and aromas) to plants such as eucalyptus, cinnamon, ginger, cloves, tomatoes, and more. As you probably know, each of those plants listed have tremendous health properties that range from antibacterial activity to lowering your blood sugar.
So what about this symplocos racemosa plant? What do its triterpenoids do? What ARE its triterpenoids?
The good news is that nearly all of the sympolocos racemosa’s triterpenoids sound great for the supplement world. This includes ursolic acid, oleanic acid, and betulinic acid.
The bad news is that we have absolutely no clue which ones, specifically, USPLabs is targeting with Compound 20, and if it will be the same from batch to batch. I’ll assume that they have their extraction process in place to get the same.
One hint is that the study sited in the official Compound 20 product description cites information from an Ursolic Acid study. What this study says is that Ursolic Acid enhances insulin/IGF-1 and signaling in skeletal muscles by quickly reducing adiposity (fatty tissue in animals), your blood sugar, and plasma cholesterol and triglycerides.
Basically, THIS is what is shuttling your carbs into your muscles and putting your fat to work in Compound 20! This is why you’re thirsty when you take it!
However, when asked, USPLabs has stated that they are not SPECIFICALLY targeting just Ursolic Acid – they are only citing the study as a reference of some of the things that triterpenoids are capable of.
Further, they stated that if you’re already supplementing something with ursolic acid in it, you can cut its dosage in half while on Compound 20. Such a supplement is Ursobolic, from a smaller company named E-pharm Nutrition.
But what USPLabs does NOT do is tell you about the awesome oleanic acid and betulinic acid that are also part of racemosa’s triterpenoid family.
Betulinic Acid helps prevent the gain of abdominal fat when taken with a high fat diet. The study shows that this has a great antiobese potential through modulation of fat and carbohydrate metabolism, but for us…
…this means that we can have a DIRTY BULK DIET and not gain too much fat!
Do I recommend it? Not really… but does it work? The testers who just piled the nonsense on their plate during their Compound 20 run say YES – it does work with a dirty bulk!
Also note that study is a study done on mice. Again, this was done via decreased blood glucose, plasma triglycerides, and total cholesterol – shuttling those carbs into the muscles is what makes you thirsty – and when you’re thirsty with this, that’s when you know it’s working.
Oleanic Acid basically does the same thing regarding obesity prevention by lowering blood glucose measures, but also acts as a vasodilator and cAMP activator by releasing something known as prostacyclin.
We know it’s a vasodilator thatnks to study  – this means that it opens up the veins for increased blood flow and nutrient delivery… and bigger pumps in the gym.
Prostacyclin also has incredible osteoprotective measures (protects bone structure and strength).
In short, these triterpenoids ROCK. Especially as an athlete, bodybuilder, powerlifter, overweight patient, or anyone hitting the gym hard. Further research shows their ability to fight cancer too.
The one problem is – we don’t know the ratio of any of these. We can just assume that there’s definitely a great amount of ursolic acid, and judging by how great of a nutrient partitioner Compound 20 is, the other two triterpenoids are also in there.
Is Compound 20 a Stimulant?
We’re going to see some arguments here, so here’s my take:
Coinciding with what USPLabs says, Compound 20 is not a stimulant.
While the chemical structure of N-Caffeoyldopamine may LOOK similar to other stimulants if you’re a biochemist, the fact is that it does not behave like one. The reason is because it’s a very selective beta-2 agonist – NOT a beta-1 agonist.
Clen is a stimulant because it’s simply out of control, firing all sorts of alpha and beta receptors, including beta-1 receptors, which are on your heart and your cardiovascular system.
Compound 20 is not like Clen in this regard. Beta-1 receptors don’t respond to it, and thus you don’t get the increased heartrate / cardiac output that Clen gives.
Like I’ve said before, this is an AMAZING product to take when you’re cycled off of Jack3d and all other stims. Compound 20 + Yok3d + Prime + Modern BCAA (the latter two being optional) would be an incredible caffeine-free stack.
Compound 20 Review – Ingredients Conclusion
If this isn’t enough information for you, then I really don’t know what else to say. Drop a comment below, but I’ve written enough. It’s time for you to try it and see for yourself.
How to Take Compound 20
The dosing protocol couldn’t be much easier. Just take 2 capsules with your pre-workout meal, and then 6-8 hours later, 2 more capsules.
I highly recommend a complex carbohydrate with Compound 20. Preferably oats, brown rice, or sweet potato / yams. Stay away from simple sugars and corn-based nonsense here (IMHO, you should ALWAYS stay away from corn, soy, and wheat, but that’s another book).
As noted above, Kameron Ross and some others did start bumping their dosages up to 6 capsules on workout days. I don’t recommend this unless you are extremely experienced with nutrient repartitioners and other USPLabs products and have your diet dialed in to the tee.
Follow the instructions, make your C20 last the entire month, but again… you’ll probably want to buy two.
As far as those who really want to take it fasted, have some carbs nearby in case you “go hypo” and get tired, and blast in as many BCAAs as you’re willing to afford during your fasted training.
Feel free to mix C20 with other USPLabs supplements. See our Compound 20 Stack for more info on that.
How Long to Take C20
As far as how long you can take it for, go in cycles of 6-8 weeks on, 4 weeks off, as needed before a show / trip to the beach / competition.
As you can imagine, I’m spent. This review simply got out of control. Please leave comments below.